Increased expression profile of NCSTN, Notch and PI3K/AKT3 in hidradenitis suppurativa
نویسندگان
چکیده
منابع مشابه
Confirmation by exome sequencing of the pathogenic role of NCSTN mutations in acne inversa (hidradenitis suppurativa).
TO THE EDITOR Acne inversa (AI; also known as hidradenitis suppurativa; OMIM #142690) is an autosomal dominantly inherited skin disorder characterized by recurrent draining sinuses and abscesses with subsequent scarring and chronic seepage. It mainly affects the scalp, neck, the axillae, perineum, and inframammary regions, which may lead to social embarrassment and have a profound impact on the...
متن کاملHidradenitis suppurativa.
BACKGROUND Hidradenitis suppurativa is a chronic, recurrent, suppurative cutaneous disease. Despite its incidence, optimal medical or surgical treatment remains unclear. This review describes the disease, ranging from pathogenesis to treatment and prognosis. METHODS Articles were sourced from PubMed and Medline, using the MeSH terms 'hidradenitis suppurativa' and 'acne inversa'. Selection of ...
متن کاملMicrobial profile and antibiotic susceptibility of bacteria isolated from patients with hidradenitis suppurativa
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease of unknown etiology. There is evidence that bacteria may contribute to initiating the inflammatory response in HS patients. To date, data on bacteria found in HS lesions and their resistance rates are rare. Methods: The results of bacterial cultures and antibiotic susceptibility of the isolated bacteria obtained fr...
متن کاملHidradenitis suppurativa.
Hidradenitis suppurativa is a chronic, relapsing, inflammatory disease process that primarily involves the axilla and/or inguinal region and does not manifest itself until after puberty. Typically, the process begins as a local occlusive disease of a sweat gland; secondary bacterial infection then occurs. The early stages of hidradenitis suppurativa are usually managed by the dermatologist. Onc...
متن کاملHidradenitis suppurativa
Hidradenitis suppurativa is a chronic disease characterized by recurrent, painful, deep-seated, rounded nodules and abscesses of apocrine gland-bearing skin. Subsequent suppuration, sinus tracts and hypertrophic scarring are its main features. Onset is usually after puberty, although it is most common during the third decade and may persist in old age. The disease tends to be chronic and may de...
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ژورنال
عنوان ژورنال: Journal of the European Academy of Dermatology and Venereology
سال: 2020
ISSN: 0926-9959,1468-3083
DOI: 10.1111/jdv.16962